Tanaya Chatterjee

Tanaya Chatterjee
DST WIDUSHI Senior Woman Scientist

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Research interests:

My research interests mainly focus on

1. Structural/functional studies on the proteins of Vibrio cholera

2. Protein- small molecule (peptide, drug, DNA) interaction of therapeutic relevance

3. Protein-nanoparticle interaction

Contact:

Address: Biological Sciences
Unified Academic Campus
Bose Institute
EN-80, Sector V
Bidhan Nagar
Kolkata - 700 091, India
E-Mail: tanaya[at]jcbose.ac.in
Phone: +91-33-25693273

Research:

Publications:

1) Chatterjee T, Guha D, Dhar J, Saha T, Paul D, Sa G & Chakrabarti P. Adenosine dialdehyde, a methyltransferase inhibitor, induces colorectal cancer cells apoptosis by regulating PIMT:p53 interaction. Biochem Biophys Res Commun, 684, 149134 (2023)

2) Chatterjee T, Das G, Chatterjee BK, Ghosh S & Chakrabarti P. The role of Protein-L-isoaspartyl methyltransferase (PIMT) in the supression of toxicity of the oligomeric form of Ab42, in addition to the inhibition of its fibrillization. ACS Chem Neuro 14, 2888-2901 (2023)

3) Chatterjee T, Saha T, Sarkar P, Hoque KM, Chatterjee BK & Chakrabarti P. The gold nanoparticle reduces Vibrio cholerae pathogenesis by inhibition of biofilm formation and disruption of the production and structure of cholera toxin. Colloids Surf B. Biointerfaces 204, 111811 (2021)

4) Chatterjee T, Das G, Ghosh S & Chakrabarti P. Effect of gold nanoparticles on the structure and neuroprotective function of protein L-isoaspartyl methyltransferase (PIMT). Sci. Rep. 11, 14296 (2021)

5) Chatterjee T, Das G, Chatterjee BK, Dhar J, Ghosh S & Chakrabarti P. The role of isoaspartate in fibrillation and its prevention by Protein-L-isoaspartyl methyltransferase. BBA General Subjects. 1864, 129500 (2020)

6) Jana TK, Jana SK, Kumar A, De K, Maiti R, Mandal AK, Chatterjee T, Chatterjee BK, Chakrabarti P & Chatterjee K. The antibacterial and anticancer properties of zinc oxide coated iron oxide nanotextured composites. Colloids Surf B. Biointerfaces 117, 512-519 (2019)

7) Chatterjee T, Chatterjee BK, Saha T, Hoque KM & Chakrabarti P. Structure and function of Vibrio cholerae accessory cholera enterotoxin in presence of gold nanoparticles: Dependence on morphology. Biochim. Biophys. Acta, 1861, 977-986 (2017)

8) Aoun J, Hayashi M, Sheikh IA, Sarkar P, Saha T, Ghosh P, Bhowmick R, Ghosh D, Chatterjee T, Chakrabarti P, Chakrabarti MK & Hoque KM. Anoctamin 6 contributes to Cl- secretion in Accessory Cholera Enterotoxin (Ace)-stimulated diarrhea: An essential role for phosphatidylinositol 4,5-bisphosphate (PIP2) signaling in cholera. J Biol Chem., 291, 26816-26836 (2016)

9) Chatterjee T, Sheikh IA, Chakravarty D, Chakrabarti P, Sarkar P, Saha T, Chakrabarti MK & Houque KM.  Effects of small molecule calcium-activated chloride channel inhibitors on structure and function of Accessory Cholera Enterotoxin (Ace) of Vibrio cholera. PLoS One, DOI:10.1371/journal.pone.0141283. (2015)

10) Chatterjee T, Mukherjee D , Banerjee M,  Chatterjee BK & Chakrabarti P. Crystal structure and activity of protein L-isoaspartyl-O-methyltransferase from Vibrio cholerae, and the effect of AdoHcy binding.  Arch Biochem Biophys, 583, 140-149 (2015)

11) Chatterjee T, Chatterjee BK, Majumdar D & Chakrabarti P. Antibacterial effect of silver nanoparticles and the modeling of bacterial growth kinetics using a modified Gompertz model. Biochim. Biophys. Acta, 1850, 299-306 (2015)

12) Chatterjee T, Pal A, Chakravarty D, Dey S, Saha RP & Chakrabarti P. Protein L-isoaspartyl-O-methyltransferase of Vibrio cholerae: interaction with cofactors and effect of osmolytes on unfolding. Biochimie, 95, 912-921(2013) 

13) Chatterjee T, Pal A, Dey S, Chatterjee BK & Chakrabarti  P.  Interaction of virstatin with human serum albumin: spectroscopic analysis and molecular modeling. PLoS One, 7, e37468 (2012)

14) Chatterjee T, Mukherjee D, Dey S, Pal A, Houque KM & Chakrabarti P. Accessory cholera enterotoxin, Ace, from Vibrio cholerae: structure, unfolding and virstatin binding. Biochemistry, 50, 2962-2972 (2011)  .

15) Chatterjee T, Chakraborti S, Joshi P, Singh SP, Gupta V & Chakrabarti P. Studies on the effect of zinc oxide nanoparticles on the structure of the periplasmic domain of ToxR protein of Vibrio cholera. FEBS J., 277, 4184-4194 (2010) 



 

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Recognition:

  • Member of National Academy of Science, 2017

Teaching:

Present:

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