Uday Bandyopadhyay

Uday Bandyopadhyay
Director

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Research interests:

  • Gastric ulcer and free radical biology:
    • Gastric mucosal cell signaling, apoptosis, mitochondrial biology and dynamics.
    • Wound healing, cell growth and proliferation
  • Malaria:
    • The exploration of Plasmodium falciparum proteome to identify new drug target.
    • Epigenetic and molecular biology of malaria parasite.
    • Host- parasite interaction.


Contact:

Address: Administration
Unified Academic Campus
Bose Institute
EN-80, Sector V
Bidhan Nagar
Kolkata - 700 091, India
E-Mail: director[at]jcbose.ac.in
Phone: +91-33-25693201

Research:

  • Gastric ulcer and free radical biology:
    • Gastric mucosal cell signaling, apoptosis, mitochondrial biology and dynamics.
    • Wound healing, cell growth and proliferation


  • Malaria:
    • The exploration of Plasmodium falciparum proteome to identify new drug target.
    • Epigenetic and molecular biology of malaria parasite.
    • Host- parasite interaction.




Publications:

  1. Plasmodium falciparum Alba6 exhibits DNase activity and participates in stress response. Shiladitya Nag, Chinmoy Banerjee, Manish Goyal, Asim Azhar Siddiqui, Debanjan Saha, Somnath Mazumder, Subhashis Debsharma, Saikat Pramanik, Shubhra Jyoti Saha, Rudranil De and Uday Bandyopadhyay. iScience. 2024 Mar 8;27(4):109467. doi: 10.1016/j.isci.2024.109467. eCollection 2024 Apr 19.

  2. NSAID targets SIRT3 to trigger mitochondrial dysfunction and gastric cancer cell death. Subhashis Debsharma , Saikat Pramanik , Samik Bindu , Somnath Mazumder , Troyee Das , Uttam Pal , Debanjan Saha , Rudranil De , Shiladitya Nag , Chinmoy Banerjee , Nakul Chandra Maiti , Zhumur Ghosh , Uday Bandyopadhyay. iScience. 2024 Mar 1;27(4):109384.doi: 10.1016/j.isci.2024.109384. eCollection 2024 Apr 19.

  3. Nuclease activity of Plasmodium falciparum Alba family protein PfAlba3. Chinmoy Banerjee, Shiladitya Nag, Manish Goyal, Debanjan Saha, Asim Azhar Siddiqui, Somnath Mazumder, Subhashis Debsharma, Saikat Pramanik, Uday Bandyopadhyay. Cell Reports, 42 (4), 112292, 2023

  4. Honokiol, an inducer of Sirtuin 3, protects against NSAID-induced gastric mucosal mitochondrial pathology, apoptosis and inflammatory tissue injury. Subhashis Debsharma , Saikat Pramanik , Samik Bindu , Somnath Mazumder , Troyee Das , Debanjan Saha , Rudranil De , Shiladitya Nag , Chinmoy Banerjee , Asim Azhar Siddiqui , Zhumur Ghosh , Uday Bandyopadhyay. Br J Pharmacol, doi: 10.1111/bph.16070 , 2023 Mar 13. . Online ahead of print.

  5. Emerging role of mitochondrial DAMPs, aberrant mitochondrial dynamics and anomalous mitophagy in gut mucosal pathogenesis. Mazumder S, Bindu S, De R, Debsharma S, Pramanik S, Bandyopadhyay U. Life Sci. Sep 15;305:120753, 2022

  6. Mediators of mitophagy that regulate mitochondrial quality control play crucial role in diverse pathophysiology. Rudranil De , Somnath Mazumder , Uday Bandyopadhyay. Cell Biol Toxicol. 37:333-366, 2021

  7. Rab7 of Plasmodium falciparum is involved in its retromer complex assembly near the digestive vacuole. Asim Azhar Siddiqui , Debanjan Saha , Mohd Shameel Iqbal , Shubhra Jyoti Saha , Souvik Sarkar , Chinmoy Banerjee , Shiladitya Nag , Somnath Mazumder , Rudranil De , Saikat Pramanik , Subhashis Debsharma , Uday Bandyopadhyay. Biochim Biophys Acta Gen Subj; 1864:129656, 2020

  8. Sirtuins as endogenous regulators of lung fibrosis: A current perspective Somnath Mazumder , Mukta Barman , Uday Bandyopadhyay , Samik Bindu. Life Sci; 258:118201, 2020

  9. Non-steroidal anti-inflammatory drugs (NSAIDs) and organ damage: A current perspective Samik Bindu , Somnath Mazumder , Uday Bandyopadhyay . Biochem Pharmacol; 180:114147. 2020.

  10. Indomethacin impairs mitochondrial dynamics by activating the PKCζ-p38-DRP1 pathway and inducing apoptosis in gastric cancer and normal mucosal cells. Somnath Mazumder , Rudranil De , Subhashis Debsharma , Samik Bindu , Pallab Maity , Souvik Sarkar , Shubhra Jyoti Saha , Asim Azhar Siddiqui , Chinmoy Banerjee , Shiladitya Nag , Debanjan Saha , Saikat Pramanik , Kalyan Mitra , Uday Bandyopadhyay. J Biol Chem; 17;294 :8238-8258, 2019.

  11. Hydrazonophenol, a food vacuole targeted and ferriprotoporphyrin IX-interacting chemotype prevents drug resistant malaria. Saha SJ, Siddiqui AA, Pramanik S, Saha D, De R, Mazumder S, Debsharma S, Nag S, Banerjee C, Bandyopadhyay U. ACS Infect Dis. 5, 63-73, 2019

  12. Macrophage migration inhibitory factor regulates mitochondrial dynamics and cell growth of human cancer cell lines through CD74-NF-κB signaling. De R, Sarkar S, Mazumder S, Debsharma S, Siddiqui AA, Saha SJ, Banerjee C, Nag S, Saha D, Pramanik S, Bandyopadhyay U. J Biol Chem. ;293:19740-19760. 2018

  13. Detection of retromer assembly in Plasmodium falciparum by immunosensing coupled to Surface Plasmon Resonance. Mohd Shameel Iqbal, Asim Azhar Siddiqui, Chinmoy Banerjee, Shiladitya Nag, Somnath Mazumder, Rudranil De, Shubhra Jyoti Saha, Suresh Kumar Karri, Uday Bandyopadhyaya. BBA - Proteins and Proteomics. 1866, 722-730, 2018.

  14. Acute mental stress induces mitochondrial bioenergetic crisis and hyper-fission along with aberrant mitophagy in the gut mucosa in rodent model of stress-related mucosal disease. De R, Mazumder S, Sarkar S, Debsharma S, Siddiqui AA, Saha SJ, Banerjee C, Nag S, Saha D, Bandyopadhyay U. Free Radic Biol Med. 113, 424-438, 2017

  15. Management of Inflammation by Natural Polyphenols: a Comprehensive Mechanistic Update. Sarkar S, Mazumder S, Saha SJ, Bandyopadhyay U. Curr Med Chem.2016, 23, 1657-1695, 2016

  16. Selective scavenging of intra-mitochondrial superoxide corrects diclofenac-induced mitochondrial dysfunction and gastric injury: A novel gastroprotective mechanism independent of gastric acid suppression. Mazumder S, De R, Sarkar S, Siddiqui AA, Saha SJ, Banerjee C, Iqbal MS, Nag S, Debsharma S, Bandyopadhyay U. Biochem Pharmacol. 121, 33-52, 2016.

  17. Antimalarial activity of small molecule benzothiazole hydrazones. Sarkar S, Siddiqui AA, Saha SJ, De R, Mazumder S, Banerjee C, Iqbal MS, Nag S, Adhikari S, Bandyopadhyay U. Antimicrob Agents Chemother. 60 :4217-4228, 2016

  18. The Alba protein family: Structure and function. Goyal M, Banerjee C, Nag S, Bandyopadhyay U. Biochim Biophys Acta. 1864(5):570-83. 2016.

  19. Expression, purification and characterization of Plasmodium falciparum vacuolar protein sorting 29. Mohd. Shameel Iqbal, Asim Azhar Siddiqui, Athar Alam, Manish Goyal, Chinmoy Banerjee, Souvik Sarkar, Somnath Mazumder, Rudranil De, Shiladitya Nag, Shubhra Jyoti Saha, Uday Bandyopadhyay. Protein. Expr. Purif 120, 7-15, 2016.

  20. Ellagic Acid, a Dietary Polyphenol, Inhibits Tautomerase Activity of Human Macrophage Migration Inhibitory Factor and Its Pro-inflammatory Responses in Human Peripheral Blood Mononuclear Cells. Sarkar S, Siddiqui AA, Mazumder S, De R, Saha SJ, Banerjee C, Iqbal MS, Adhikari S, Alam A, Roy S, Bandyopadhyay U. J. Agric. Food. Chem.63(20):4988-98, 2015.

  21. TALEN mediated targeted editing of GM2/GD2-synthase gene modulates anchorage independent growth by reducing anoikis resistance in mouse tumor cells. Mahata B, Banerjee A, Kundu M, Bandyopadhyay U, Biswas K. Sci Rep. 12; 5: 9048, 2015.

  22. Trisubstituted Methanes (TRSMs): Synthesis and Bioevaluation as Anti-malarials Manna, S.K., Singh, P., Mondal, S., Goyal. M. Bandyopadhyay, U., and Panda, G. SOP Trans Org Chem,1,8-20, 2014.

  23. Association of heme oxygenase 1 with the restoration of liver function after damage in murine malaria by Plasmodium yoelii. Sumanta Dey, Somnath Mazumder, Asim Azhar Siddiqui, Mohd. Shameel Iqbal, Chinmoy Banerjee, Souvik Sarkar, Rudranil De, Manish Goyal, Samik Bindu and Uday Bandyopadhyay. Infect. Immun. 82, 3113-26, 2014.

  24. Nonsteroidal anti-inflammatory drug induces proinflammatory damage in gastric mucosa through NF-κB activation and neutrophil infiltration: Anti-inflammatory role of heme oxygenase-1 against nonsteroidal anti-inflammatory drug. Bindu S, Mazumder S, Dey S, Pal C, Goyal M, Alam A, Iqbal MS, Sarkar S, Azhar Siddiqui A, Banerjee C, Bandyopadhyay U. Free Radic Biol Med. 65C:456-467, 2013.

  25. Synthesis and biological evaluation of primaquine–chloroquine twin drug: a novel heme-interacting molecule prevents free heme and hydroxyl radical-mediated protein degradation. Chinmay Pal , Souvik Sarkar , Somnath Mazumder , Susanta Adhikari and Uday Bandyopadhyay. Med. Chem. Commun. 4, 731–736, 2013.

  26. Impact of Intravascular Hemolysis in Malaria on Liver Dysfunction: Involvement of Hepatic Free Heme Over-load, NFB Activation and Neutrophil Infiltration. Sumanta Dey, Samik Bindu, Manish Goyal, Chinmay Pal, Athar Alam, Mohd. Shameel Iqbal, Rahul Kumar, Souvik Sarkar, and Uday Bandyopadhyay. J. Biol. Chem. Aug 3; 287(32):26630-46, 2012.

  27. Novel anti-inflammatory activity of epoxyazadiradione against macrophage migration inhibitory factor: inhibition of tautomerase and pro-inflammatory activities of macrophage migration inhibitory factor. Alam A, Haldar S, Thulasiram HV, Kumar R, Goyal M, Iqbal MS, Pal C, Dey S, Bindu S, Sarkar S, Pal U, Maiti NC, Bandyopadhyay U. J. Biol. Chem. Jul 13;287(29):24844-61, 2012.

  28. Aryl aryl methyl thio arenes prevent multidrug-resistant malaria in mouse by promoting oxidative stress in parasites. Goyal M, Singh P, Alam A, Kumar Das S, Shameel Iqbal M, Dey S, Bindu S, Pal C, Kumar Das S, Panda G, Bandyopadhyay U. Free Radic Biol Med. 53, 129-142, 2012.

  29. Identification and molecular characterization of an Alba-family protein from human malaria parasite Plasmodium falciparum. Goyal M, Alam A, Iqbal MS, Dey S, Bindu S, Pal C, Banerjee A, Chakrabarti S, Bandyopadhyay U. Nucleic Acids Res. Feb 1;40(3):1174-90, 2012.

  30. Redox regulation in malaria: current concepts and pharmacotherapeutic implications. Goyal M, Alam A, Bandyopadhyay U. Curr. Med. Chem.;19 :1475-503. 2012.

  31. Redox-active antiparasitic drugs. Pal C, Bandyopadhyay U. Antioxid Redox Signal., 17, 555-581, 2012

  32. Synthesis and bio-evaluation of human macrophage migration inhibitory factor inhibitor to develop anti-inflammatory agent. Alam A, Pal C, Goyal M, Kundu MK, Kumar R, Iqbal MS, Dey S, Bindu S, Sarkar S, Pal U, Maiti NC, Adhikari S, Bandyopadhyay U. Bioorg. Med. Chem., 19(24):7365-73, 2011.

  33. Translocation of heme oxygenase-1 to mitochondria is a novel cytoprotective mechanism against non-steroidal anti-inflammatory drug-induced mitochondrial oxidative stress, apoptosis and gastric mucosal injury. Bindu S, Pal C, Dey S, Goyal M, Alam A, Iqbal MS, Dutta S, Sarkar S, Kumar R, Maity P, Bandyopadhyay U. J. Biol. Chem. 286, 39387-39402, 2011.

  34. Synthesis of novel heme-interacting acridone derivatives to prevent free heme-mediated protein oxidation and degradation. Chinmay Pal, Milan Kumar Kundu, Uday Bandyopadhyay, Susanta Adhikari. Bioorg. Med. Chem. Lett, 21 3563-3567, 2011.

  35. Cysteine-3 and cysteine-4 are essential for the thioredoxin-like oxidoreductase and antioxidant activities of Plasmodium falciparum macrophage migration inhibitory factor. Alam A, Goyal M, Iqbal MS, Bindu S, Dey S, Pal C, Maity P, Mascarenhas NM, Ghoshal N, Bandyopadhyay U. Free. Radic. Biol. Med, 50 1659–1668, 2011.

  36. Gallic acid prevents non-steroidal anti-inflammatory drug-induced gastropathy in rat by blocking oxidative stress and apoptosis. Chinmay Pal, Samik Bindu, Sumanta Dey, Athar Alam, Manish Goyal, Mohd.Shameel Iqbal, Pallab Maity, Susanta S. Adhikari, Uday Bandyopadhyay. Free. Radic. Biol. Med. 49, 258-267, 2010.

  37. Indomethacin, a non-steroidal anti-inflammatory drug, develops gastropathy by inducing reactive oxygen species-mediated mitochondrial pathology and associated apoptosis in gastric mucosa: A novel role of mitochondrial aconitase oxidation. Maity P, Bindu S, Dey S, Goyal M, Alam A, Pal C, Mitra K, Bandyopadhyay U. J. Biol. Chem. 284: 3058-3068, 2009.

  38. The use of Neem for controlling gastric hyperacidity and ulcer. Maity P, Biswas K, Chattopadhyay I, Banerjee RK, Bandyopadhyay U. Phytother Res. 23 747-755, 2009

  39. Malarial infection develops mitochondrial pathology and mitochondrial oxidative stress to promote hepatocyte apoptosis. Sumanta Dey, Mithu Guha, Athar Alam, Manish Goyal, Samik Bindu, Chinmay Pal, Pallab Maity, Kalyan Mitra and Uday Bandyopadhyay. Free. Radic. Biol. Med. 46, 271-281, 2009.

  40. Novel antimalarial drug targets: Hope for new antimalarial drug. Athar Alam, Manish Goyal, Mohd Shameel Iqbal, Chinmay Pal, Sumanta Dey, Samik Bindu, Pallab Maity, Uday Bandyopadhyay. Expert. Rev.Clin. Pharmacol. 2, 469-489, 2009

  41. Melatonin reduces indomethacin-induced gastric mucosal cell apoptosis by preventing mitochondrial oxidative stress and the activation of mitochondrial pathway of apoptosis. Maity P, Bindu S, Dey S, Goyal M., Alam A, Pal C, Reiter R and Bandyopadhyay U. J. Pineal. Res. 46: 314-23, 2009.

  42. Biological activities of crude extracts and chemical constituents of Bael, Aegle marmelos (L.) Corr. Pallab Maity, Dhananjay Hansda, Uday Bandyopadhyay, Dipak Mishra. Ind. J. Exp. Biol 47: 849-861, 2009

  43. Bilirubin inhibits Plasmodium falciparum growth through the generation of reactive oxygen species. S Kumar, M Guha, V Choubey, P Maity, K Shrivastava, S K Puri and U Bandyopadhyay. Free. Radic. Biol. Med. 44: 602-613, 2008.

  44. Antiplasmodial activity of [(Aryl)arylsulfanylmethyl]Pyridine S Kumar, S K Das,S Dey,P Maity, M Guha, V Choubey, G Panda, and U Bandyopadhyay. Antimicrob Agents Chemother. 52: 705-715, 2008.

  45. Melatonin inhibits free radical-mediated mitochondrial-dependent hepatocyte apoptosis and liver damage induced during malarial infection M Guha, P Maity, K Mitra,R J Reiter, and U Bandyopadhyay. J. Pineal. Research. 43: (2007), 373-381.

  46. Antimalarial drugs inhibiting hemozoin (β hematin) formation: A mechanistic update. Sanjay Kumar, Mithu Guha, Vinay Choubey, Pallab Maity, Uday Bandyopadhyay (2007) Life. Sciences. 80, 813-828.

  47. Inhibition of Plasmodium falciparum choline kinase by hexadecyltrimethylammonium bromide: A possible antimalarial mechanism of hexadecyltrimethylammonium bromide. V Choubey, P Maity, M Guha, S Kumar, K Shrivastava, S K Puri and U Bandyopadhyay. Antimicrob. Agents. Chemother. 51: 696-706, 2007.

  48. Overexpression, purification and localization of apoptosis related protein from Plasmodium falciparum. Mithu Guha, Vinay Choubey, Pallab Maity, Sanjay Kumar, Kumkum Shrivastava, Sunil K. Puri and Uday Bandyopadhyay. Protein Expr. Purif. 52, 363-372, 2007.

  49. Apoptosis in liver during malaria: Role of oxidative stress and implication of mitochondrial pathway. Mithu Guha, Sanjay Kumar, Vinay Choubey, Pallab Maity and Uday Bandyopadhyay FASEB. J, 20, 1224-1226, 2006.

  50. Molecular characterization and localization of Plasmodium falciparum choline kinase. Choubey, V., Guha, M., Maity, M., Kumar, S., Raghunandan, R., Maulik, P. R., Mitra, K., Halder, U. C. and Uday Bandyopadhyay. Biochim. Biophys. Acta. 1760, 1027-1038, 2006.

  51. Indomethacin inactivates gastric peroxidase to induce reactive oxygen-mediated gastric mucosal injury and curcumin protects it by preventing peroxidase inactivation and scavenging reactive oxyge. Chattopadhyay, I., Bandyopadhyay, U., Biswas, K., Maity, M., and Banerjee, R.K. Free. Radic. Biol. Med. 40, 1397-1408, 2006.

  52. Mechanism of horseradish peroxidase-catalyzed heme oxidation and polymerization (beta-hematin formation). V. Trivedi, Prem Chand, P. R. Maulik, and U. Bandyopadhyay. Biochim. Biophys. Acta. 1723, 221-228, 2005.

  53. Clotrimazole Inhibits Hemo- peroxidase of P. falciparum and Induces Oxidative Stress: PROPOSED ANTIMALARIAL MECHANISM OF CLOTRIMAZOLE. Vishal Trivedi ,Prem Chand, Kumkum Srivastava, Sunil K. Puri, Prakas R. Maulik, and Uday Bandyopadhyay J. Biol. Chem. 280, 41129-41136, 2005.

  54. Purification and biochemical characterization of a heme containing peroxidase from the human parasite P. falciparum. V. Trivedi, K. Srivastava, S. K. Puri, P. R. Maulik, and U. Bandyopadhyay. Protein. Expr. Purif. 41, 154-161, 2005.

  55. Free heme toxicity and its detoxification systems in human. S. Kumar and U. Bandyopadhyay Toxicol. Lett. 157, 175-188, 2005

  56. Clinical studies on the effect of Neem (Azadirachta indica) bark extract on gastric secretion and gastroduodenal ulcer. U. Bandyopadhyay, A. Sengupta, P. Moitra, P. Dutta, D. Sarkar, P. Debnath and R. K. Banerjee. Life Sciences, 75, 2867-2878, 2004.

  57. Turmeric and curcumin: Biological actions and medicinal applications. I. Chattopadhyay K. Biswas, U. Bandyopadhyay, and R.K. Banerjee Current Science, 87, 44-53, 2004

  58. Mechanism of antiulcer effect of Neem (Azadirachta indica) leaf extract: effect on H+-K+- ATPase, oxidative damage and apoptosis. I. Chattopadhyay, B. Nandi, R. Chatterjee, K. Biswas, U. Bandyopadhyay, and R.K. Banerjee. Inflammopharmacology, 12, 153-176, 2004.

  59. Smoking and the pathogenesis of gastro-duodenal ulcer – a recent mechanistic update. P. Maity, K. Biswas, S. Roy, R. K. Banerjee and U. Bandyopadhyay Mol. Cell. Biochem. 253, 329-338, 2004

  60. A novel antioxidant and antiapoptotic role of omeprazole to block gastric ulcer through scavenging of hydroxyl radical. K Biswas, Bandyopadhyay U, I. Chatterjee, A. Varadaraj, E. Ali and Banerjee R. K J. Biol. Chem., 278, 10990- 11001, 2003.

  61. Gastroprotective effect of Neem (Azadirachta indica) bark extract through inhibition of H+-K+-ATPase and scavenging of hydroxyl radical. U. Bandyopadhyay, K. Biswas, R. Chatterjee, D Bandyopadhyay, I Chattopadhyay C. K. Ganguly, T.K. Chakraborty, K Bhattacharya and R.K. Banerjee. Life Sciences. 71: 2845-2865, 2002.

  62. Probing the role of active site histidine residues in thiocyanate oxidation by lacrymal gland peroxidase. A. Mazumdar, D. Bandyopadhyay, U. Bandyopadhyay and R. K. Banerjee. Mol. Cell. Biochem. 237: 21-30. 2002.

  63. Extrathyroidal actions of antithyroid thionamides. U. Bandyopadhyay, K. Biswas, and R K. Banerjee. Toxicology Letts. 128: 117-128, 2002

  64. Biological activities and medicinal properties of Neem (Azadirachta indica ). K Biswas, I. Chatterjee, R. K Banerjee and U. Bandyopadhyay. Current Science. 82:, 1336-1345, 2002

  65. An essential role of an active site arginine in iodide binding and histidine residue in electron transfer for iodide oxidation by HRP. S. Adak, D. Bandyopadhyay, U. Bandyopadhyay and R. K. Banerjee. Mol. Cell. Biochem. 218: 1-11, 2001.

  66. Melatonin protects against stress-induced gastric lesions by scavenging the hydroxyl radical. D Bandyopadhyay, K Biswas, U Bandyopadhyay, R J. Reiter and R K. Banerjee. J. Pineal. Research. 29: 143-151, 2000.

  67. Delineation of the insulin-response sequence in the rat cytosolic aspartate aminotransferase gene: binding sites for hepatocyte nuclear factor-3 and nuclear factor1. F Beurton, U Bandyopadhyay, B Dieumegard, R Barouki and M Aggerbeck. Biochem. J. 343: 687-695, 1999.

  68. Role of active site residues in peroxidase catalysis: Studies on Horseradish peroxidase. U Bandyopadhyay, S Adak, and R K Banerjee. Proc. Ind. Natl. Sci. Acad. B 65: 315-330, 1999

  69. Dexamethasone makes the gastric mucosa susceptible to gastric ulceration by inhibiting prostaglandin synthetase and peroxidase- two important gastroprotective enzymes. U Bandyopadhyay, K Biswas, D Bandyopadhyay, C K Ganguly and R K Banerjee. Mol. Cell. Biochem. 202: 31-36, 1999.

  70. Role of reactive oxygen species in mercaptomethylimidazole-induced gastric acid secretion and stress-induced gastric ulceration U. Bandyopadhyay, D Das, D Bandyopadhyay, M Bhattacharjee and R K Banerjee. Current Science. 76: 55-63, 1999

  71. Reactive oxygen species-oxidative damage and pathogenesis. U. Bandyopadhyay, D Das and R. K. Banerjee, Current Science. 77: 658-666, 1999

  72. Mechanism of horseradish peroxidase catalysed epinephrine oxidation- obligatory role of endogenous O2- and H2O2. S. Adak, U. Bandyopadhyay, D Bandyopadhyay and R.K Banerjee. Biochemistry. 37: 16922-16933, 1998.

  73. Vicinal thiols are involved in inositol 1,2,3,5,6-pentakisphosphate 5-phosphatase activity from fetal calf thymas. U. Bandyopadhyay, T Kaiser, T M Rudolf, C Schultz, A H Guse, and G W Mayr. Biochem. Biophys. Res. Commun. 240: 146-149, 1997.

  74. Activation of Parietal cell by Mercaptomethylimidazole- a Novel Inducer of Gastric acid secretion. U. Bandyopadhyay, R, Chatterjee, T.K. Chakraborty, C.K. Ganguly, D.K. Bhattacharyya, and R. K. Banerjee. Biochem. Pharmacol. 54: 241-248, 1997.

  75. EDTA inhibits lactoperoxidase- catalyzed iodide oxidation by acting as an electron doner and interacting near the iodide-binding site. D K Bhattacharyya, U Bandyopadhyay, and R. K. Banerjee. Mol. Cell. Biochem. 162: 105-111, 1996.

  76. Lactoperoxidase-catalysed oxidation of indomethacin, a nonsteroidal antiinflammatory drug, through the formation of a free radical. R. Chatterjee, U. Bandyopadhyay, A. Mazumdar and R. K. Banerjee. Biochem. Pharmacol, 52: 1169-1175, 1996.

  77. Concurrent reduction of iodine and oxidation of EDTA at the active site of horseradish perosidase : probing the iodine binding site by optical difference spectroscopy and steady state kinetic analysis for the formation of active enzyme 1-EDTA ternary complex for iodine reductase activity. S. Adak, D. Kr. Bhattacharyya ,U. Bandyopadhyay and R. K. Banerjee . Biochemistry. 34: 12998-13006, 1995.

  78. Irreversible inactivation of lactoperoxidase by mercaptomethylimidazole through generation of thiylradical: its use as a probe to study the active site. U. Bandyopadhyay, D. Kr. Bhattacharyya, R. Chatterjee. and R. K. Banerjee. Biochem. J. 306: 751-758, 1995.

  79. On the mechanism of inhibition of horseradish peroxidase catalysed iodide oxidation by EDTA. D. Kr. Bhattacharyya, S. Adak, U. Bandyopadhyay and R.K. Banerjee. Biochem. J. 298: 281-288, 1994.

  80. Inhibition of intestinal peroxidase activity by nonsteroidal anti-inflammatory drugs. R. Chatterjee, U. Bandyopadhyay, D. Kr. Bhattacharyya and R.K. Banerjee. Biochim. Biophys. Acta. 1161: 168-176, 1993.

  81. Chemical and kinetic evidence for an essential histidine residue in the electron transfer from aromatic doner to horseradish peroxidase compound 1. D Kr Bhattacharyya, U. Bandyopadhyay and R. K. Banerjee. J. Biol. Chem. 268: 22292-22298, 1993.

  82. Iodide modulates the EDTA-induced iodine reductase activity of the horseradish peroxidase by interacting at or near EDTA binding site. D. Kr Bhattacharyya, U. Bandyopadhyay, R. Chatterjee and R. K. Banerjee. Biochem. J, 289: 575-580, 1993.

  83. Effect of dexamethasone on the peptic activity of gastric lumen and mucosa. U. Bandyopadhyay, D. Kr. Bhattacharyya, R. Chatterjee, T. Chakraborty and R. K. Banerjee. Biochem. Pharmacol. 45: 879-883, 1993.

  84. Mechanism based inhibition of gastric peroxidase by mercaptomethylimidazole. U. Bandyopadhyay, D. Kr. Bhattacharyya and R. K. Banerjee. Biochem. J, 296: 79-84, 1993.

  85. Localization of gastric peroxidase and its inhibition by mercaptomethylimidazole, an inducer of gastric acid secretion. U. Bandyopadhyay, D. Kr Bhattacharyya, R.Chatterjee and R. K. Banerjee. Biochem. J, 284: 305-312, 1992.

  86. Chemical and kinetic evidence for an essential histidine in horseradish peroxidase for iodide oxidation. D Kr Bhattacharyya, U. Bandyopadhyay and R. K. Banerjee. J. Biol. Chem. 267: 9800-9804, 1992.


NUMBER OF BOOKS AUTHORED/EDITED:

1.     Phytochemical and human health (editors:  A. Farouki and T Farouki): Beneficial effects of Neem.  Uday Bandyopadhyay and Samik Bindu, Chapter VII, page 187-218, Nova Science publishers, Inc, New York, 2011.

2.    Apicomplexan Parasites: Molecular Approaches Toward Targeted Drug Development (editor K. Becker); Antimalarial drugs and molecules inhibiting hemozoin formation Bandyopadhyay, U.; Dey, S. Wiley-VCH, Germany, 2011, 2, 205-234.
 


NUMBER OF PATENTS GRANTED:

1.    USA Patent:  Tryptamine derivatives, their preparation and their use in gastropathy. Bandyopadhyay Uday, Pal Chinmay, Bindu Samik, Adhikari Susanta Sekhar, Grant date 02/12/2014, Patent No: US8,901317B2.

2.    European Patent: Tryptamine derivatives, their preparation and their use in gastropathy. Bandyopadhyay Uday, Pal Chinmay, Bindu Samik, Adhikari Susanta Sekhar,   Grant date 16/12/2015, Patent No: 2616439.

3.    Japanese Patent: Tryptamine derivatives, their preparation and their use in gastropathy. Bandyopadhyay Uday, Pal Chinmay, Bindu Samik, Adhikari Susanta Sekhar, Grant date 15/01/2016, Patent No: 5868980.


4.    USA Patent: A process for the isolation of active principle from Azadirachta indica useful for controlling gastric hyperacidity and gastric ulceration, U Bandyopadhyay, R Chatterjee, RK Banerjee Grant date 24/03/1998, Patent No: 5730986.

5.    European Patent: A process for the isolation of active principle from Azadirachta indica useful for controlling gastric hyperacidity and gastric ulceration, U Bandyopadhyay, R Chatterjee, RK Banerjee Grant date 24/04/2005, Patent No: EP0787495 B1.

6.    Indian Patent: A process for the isolation of active principle from Azadirachta indica useful for controlling gastric hyperacidity and gastric ulceration, U Bandyopadhyay, R Chatterjee, RK Banerjee Grant date 01/08/2003, Patent No: 188667.

7.    Japanese Patent: A process for the isolation of active principle from Azadirachta indica useful for controlling gastric hyperacidity and gastric ulceration, U Bandyopadhyay, R Chatterjee, RK Banerjee Grant date 15/03/2002, Patent No: 3286778.

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Recognition:

  • J.C. Bose National Fellowship , 2015
  • Fellow of Indian National Science Academy (FNA), 2014
  • Fellow of Indian Academy of Sciences (FASc), 2013
  • Fellow of the National Academy of Sciences (FNASc), India , 2008
  • Humboldt Fellowship (Alexander Von Humboldt Foundation, Germany), 1996
  • INSERM Fellowship, Paris, France, 1995
  • Fellow of the West Bengal Academy of Science and Technology (FAScT) , 2009
  • Young Scientist Award from International Union of Biochemistry and Molecular Biology (IUBMB), 1994
  • Professor R. C. Shah Memorial Award, 96th Indian Science Congress, 2009
  • Professor A. N. Bhaduri Memorial Lecture Award from the Society of Biological Chemist (India), 2012

Teaching:

Students:

Image Name Designation Department Campus Contact number Email
profile image Chinmoy Banerjee Senior Project Associate Division of Molecular Medicine Centenary chinmoybanerjee.7@gmail.com
profile image Shiladitya Nag Project Associate - II Division of Molecular Medicine Centenary shiladitya_nag@yahoo.co.in

Former:

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